Introduction: �Nā ʻiʻo

Aia 3 ʻano ʻano hopena maikaʻi ʻole i nā protein palaoa, i ʻike pū ʻia ʻo ka wheat protein reactivity: wheat allergy (WA), gluten sensitivity (GS), a me celiac disease (CD). ʻO ka 3, ʻo CD wale nō ka mea i ʻike ʻia e pili ana i ka reactivity autoimmune, ka hana ʻana o nā antibodies, a me ka pōʻino mucosal intestinal. ʻO ka maʻi maʻi palaoa e pili ana i ka hoʻokuʻu ʻana o ka histamine ma ke ala o ka immunoglobulin (Ig) E hoʻopili ʻia me nā peptides gluten a loaʻa i loko o nā hola ma hope o ka ʻai ʻana i nā protein palaoa. Ua manaʻo ʻia ʻo Gluten sensitivity he hōʻailona o ka wehe ʻana; Hoʻomaikaʻi ka poʻe maʻi i ka hōʻailona me ka ʻai ʻole gluten (GFD) akā ʻaʻole hōʻike i nā antibodies a i ʻole IgE reactivity.1

ʻO ka pākuʻi pūʻia o WA he mea helu. ʻO nā laina pākuʻi mai 0.4% i ka 9% o ka heluna.2,3 He mea paʻakikī kaʻikeʻole o ka GS, no ka meaʻaʻole ia he wehewehe kūlana aʻo ia ka hōʻailona o ka hoʻoneʻe. ʻO ke kūlana kūpono o ka 0.55% ma muli o ka National Health and Nutrition Examination Survey ma ka 2009 a hiki i ka 2010.4 Ma kahi o ka 2011 aʻo, ua hōʻikeʻia kahi GS o 10% ma ka helu US.5 Heʻokoʻa me nā hiʻohiʻona 2 i hōʻikeʻia nei, ua maikaʻi ka CD. wehewehe. Uaʻikeʻia ka hōʻikeʻana o 2012 i nā maʻi maʻamau mai nā poʻe 7798 ma ka National Health and Nutrition Examination Survey ma kaʻikeʻana i ka 2009 a hiki i ka 2010 i loaʻa ka 0.71% maʻamau i ka United States.6

Ua kākau maikaʻi ʻia nā hōʻike neurologic e pili ana me nā hopena maikaʻi ʻole i nā protein palaoa. Ma mua o ka makahiki 1908, ua manaʻo ʻia e pili ana ka �neuritis peripheral� me CD.7 Ua hōʻike ʻia kahi loiloi o nā haʻawina i paʻi ʻia e pili ana i kēia kumuhana mai 1964 a i 2000 ʻo nā hōʻike neurologic maʻamau e pili ana me GS he ataxia (35%), peripheral neuropathy (35%), a me ka myopathy (16%). 8 ʻO nā poʻo, paresthesia, hyporeflexia, nāwaliwali, a me ka hoʻohaʻahaʻa haʻalulu vibratory i hōʻike ʻia e ʻoi aku ka nui o nā maʻi CD vs controls.9 ʻO kēia mau hōʻailona like i ʻoi aku ka nui o nā maʻi CD i hahai ʻole i kahi GFD vs ka poʻe i hoʻokō me GFD.

I kēia manawa,ʻaʻohe pūʻulu hōʻike e hōʻike ana i ka mālamaʻana o ka maʻi maʻi i ka neuropathy. No laila,ʻo ke kumu o kēia hihia hihia, e wehewehe i kahi hōʻike hoʻomanawanui o ka mea i manaʻoʻia gluten neuropathy a me kahi hana maʻamau e hoʻohana ai i ka hoʻomaikaʻi hou.

Kūkākākā

Ua hōʻike ʻia kahi kanaka 28 makahiki i kahi keʻena aʻo chiropractic me nā hoʻopiʻi no ka hoʻomaʻamaʻa ʻana i nā ʻiʻo mau o 2 mau makahiki. Ua hoʻomaka mua ka ʻiʻo ma ka maka hema a noho ma laila no 6 mau mahina. Ua ʻike ka mea maʻi ua hoʻomaka nā fasciculations e neʻe i nā wahi ʻē aʻe o kona kino. Ua neʻe mua lākou i ka maka ʻākau, a ma hope o nā lehelehe, a laila i nā keiki bipi, quadriceps, a me nā ʻiʻo gluteus. I kekahi manawa, hiki mai ka ʻiʻo i loko o ka ʻiʻo hoʻokahi a i ʻole ke komo ʻana o nā ʻiʻo āpau i luna i ka manawa like. Me ka ʻūhā ʻana, hōʻike ʻo ia i ka manaʻo "huhū" mau a "kolo" ma kona mau wāwae. ʻAʻohe wahi i ke ao a i ka pō i pau ai ka ʻōhumu.

Ua ʻōlelo mua ka mea maʻi i ka ʻiʻo ʻana o ka ʻiʻo i ka lawe ʻana i ka caffeine (20 oz o ka kofe i ka lā) a me ke kaumaha mai ke kula. Hōʻole ka mea maʻi i ka hoʻohana ʻana i nā lāʻau lapaʻau ʻole, ka paka, a i ʻole nā ​​​​lāʻau lapaʻau ʻē aʻe akā inu ʻo ia i ka waiʻona (ka nui o ka pia) me ka maʻalahi. Ua ʻai ka mea maʻi i ka meaʻai kiʻekiʻe i nā ʻiʻo, nā huaʻai, nā mea kanu, a me ka pasta. ʻEwalu mahina ma hope o ka hoʻomaka ʻana o nā fasciculations mua, ua hoʻomaka ka mea maʻi e ʻike i ka pilikia o ka ʻōpū (GI). ʻO nā hōʻailona ʻo ia ka constipation a me ka bloating ma hope o ka ʻai ʻana. Ua hoʻomaka ʻo ia e ʻike i kāna mea i wehewehe ai ʻo `noe lolo,' ka nele o ka noʻonoʻo ʻana, a me ka manaʻo nui o ka luhi. Ua ʻike ka mea maʻi i ka wā i ʻoi aku ka maikaʻi o ka hoʻomaʻamaʻa ʻana o ka ʻiʻo, ʻoi aku ka maikaʻi o kāna mau hōʻailona GI. I kēia manawa, kau ka mea maʻi iā ia iho i kahi GFD koʻikoʻi; a i loko o 2 mahina, ua hoʻomaka nā hōʻailona e hoʻopau akā ʻaʻole i pau loa. Ua hoʻomaikaʻi nā hōʻailona GI, akā ua ʻike mau ʻo ia i ka bloating. ʻO ka ʻai a ka mea maʻi ka hapa nui o nā ʻiʻo, nā huaʻai, nā lau ʻai, nā kīʻaha gluten-free, nā hua manu, a me ka waiu.

I ka makahiki 24, ua ʻike ʻia ka mea maʻi me WA ma hope o ka ʻike ʻana i kāna kauka no ka maʻi allergies. Ua hōʻike ʻia ka hoʻāʻo ʻana i ka serum i nā antibodies IgE kiʻekiʻe e kūʻē i ka palaoa, a ua ʻōlelo ʻia ka mea maʻi e pili i kahi GFD koʻikoʻi. Ua ʻae ka mea maʻi ʻaʻole i hahai i kahi GFD a hiki i ka piʻi ʻana o kāna mau hana i ka mahina ʻo Dekemaba 2011. I Iulai o 2012, ua loiloi ʻia ka hana koko no nā pae o ka creatine kinase, creatine kinase�MB, a me ka lactate dehydrogenase e noiʻi ai i ka haki ʻana o ka ʻiʻo. Aia nā waiwai a pau i loko o nā palena maʻamau. I ka mahina o Kepakemapa o 2012, ua hoʻāʻo hou ka mea maʻi i ka maʻi ʻai (US Biotek, Seattle, WA). Ua ʻike ʻia nā pae antibody IgG kiʻekiʻe loa e kūʻē i ka waiū bipi, ka whey, ka hua moa keʻokeʻo, ka hua manu ʻeke keʻokeʻo, ka hua moa moa, ka hua manu ʻaʻa, ka bale, ka gliadin palaoa, ka gluten palaoa, ka rai, ka spell, a me ka palaoa holoʻokoʻa (Papa 1) . Hāʻawi ʻia i nā hopena o ka papa allergy meaʻai, ua ʻōlelo ʻia ka mea maʻi e wehe i kēia papa inoa o nā meaʻai mai kāna ʻai. I loko o 6 mau mahina ma hope o ka hoʻololi ʻana i ka meaʻai, ua hoʻoholo piha ʻia nā ʻiʻo o ka mea maʻi. Ua ʻike ka mea maʻi i ka liʻiliʻi loa o ka pilikia GI, ka luhi, a me ka nele o ka noʻonoʻo.

kūkākūkā

ʻAʻole i loaʻa i nā mea kākau nā haʻawina hihia i paʻi ʻia e pili ana i kahi hōʻike e like me ka mea i wehewehe ʻia ma aneʻi. Manaʻo mākou he hōʻike kūʻokoʻa kēia o ka reactivity protein wheat a no laila ke hōʻike nei i kahi hāʻawi i ke kino o ka ʻike ma kēia kahua.